News & Press: Technical News

Antiproliferative evaluation of tall-oil docosanol and tetracosanol over CHO-K1 and human melanoma c

Tuesday, May 19, 2015  
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Abstract

Background

Polycosanols derived from plant species have traditionally been used in medicine as antiproliferative agents for treating various viruses (primarily the herpes simplex virus). However, few studies have studied their effects on hyperproliferative cell lines. In this work, the antiproliferative capacity of polycosanols from tall-oil pitch, obtained from black liquor soaps in the kraft pulping process of cellulose (specifically from Pinus radiata, Pinus taede, and Eucalyptus globulus), was evaluated on CHO-K1 and CRL-1974 human melanoma cell lines.

Read more: http://www.sciencedirect.com/science/article/pii/S0717345815000676