Geraniol and α-terpineol are insoluble in water volatile compounds. α-Terpineol is a potentially important agent for medical applications. Formation of molecular complexes with β-cyclodextrin would lead to the increase of water solubility and bioavailability. β-Cyclodextrin forms 2:2 inclusion complexes with both enantiomers of α-terpineol and their precursor geraniol. Solid state complexes are thoroughly characterized by single X-ray crystallography and their stability over vast range of temperatures is proven by TG analysis. Intermolecular host–guest, host–host and guest–guest interactions give good insight into the nature of formed inclusion complexes. Stability constants of the complexes in solution are determined by HPLC.
Pine Chemicals Association International
P.O. Box 17136, Fernandina Beach, FL 32035
Phone: (404) 994-6267
The Pine Chemicals Association International (PCA) is recognized as a global leader representing, supporting and advocating for the value of Pine Chemicals as bio-renewable and sustainable products. The association is a non-profit entity with members who are producers, processors, traders, and consumers of chemicals derived from pine trees, a renewable resource.